Orchard Therapeutics Announces $150 Million Series C Financing to Advance Gene Therapy Pipeline
UCLTF funded Orchard Therapeutics, a biotechnology company dedicated to transforming the lives of patients with rare disorders through innovative gene therapies, today announced the completion of an oversubscribed $150 million Series C financing.
Deerfield Management led the financing with significant new investments from RA Capital Management, Venrock, Foresite Capital, Perceptive Advisors, Cormorant Asset Management LP, ArrowMark Partners, Sphera Global Healthcare, Medison Ventures, Driehaus Capital Management and Ghost Tree Capital Group, LP, as well as additional U.S. based healthcare focused funds. Existing investors also participated including Temasek, Baillie Gifford, RTW Investments, LP, Cowen Healthcare Investments and Agent Capital.
Proceeds from the Series C financing will be used to progress Orchard’s three most advanced clinical programs towards registration and commercialisation:
- OTL-101 for adenosine deaminase severe combined immunodeficiency (ADA-SCID)
- OTL-200 for metachromatic leukodystrophy (MLD)
- OTL-103 for Wiskott–Aldrich syndrome (WAS)
The funding will also support the clinical and pre-clinical development of the company’s rare disease gene therapy pipeline.
Mark Rothera, president and CEO of Orchard said “We are thrilled to have such strong support from both new and existing investors in this financing round. The quality of this investor syndicate is a testament to the confidence we have built among our stakeholders, based on the substantial progress of Orchard’s clinical and preclinical programs since our Series B round last year.”
Frank Thomas, CFO and chief business officer of Orchard, said "This financing provides Orchard with additional capital to rapidly progress our most advanced clinical programs to commercialization. We are advancing our pipeline of potentially transformative gene therapies in primary immune deficiencies and neurometabolic disorders to reach patients as quickly as possible.”
Elise Wang, Principal at Deerfield Management said “Orchard has made an impressive transition from a start-up company to an emerging leader in gene therapy for rare diseases by building a comprehensive, industry-leading, portfolio of ex vivo gene therapies and assembling a highly experienced team. We are pleased to have led this round of financing. We believe the company has generated compelling clinical data on products which have the potential to become breakthrough treatments for patients.”